Isotopically Labeled Compounds
Medchemexpress LLC Penicillin V-d5 | 1356837-87-0 | 99.5% | 1 MG
Penicillin V-d5 (Phenoxymethylpenicillin-d5) is the deuterium-labeled form of Penicillin V, an orally active antibiotic that inhibits the growth of Streptococci, C. difficile, and S. aureus. It is utilized in research for conditions such as otitis, sinusitis, pharyngitis, and tonsillitis.
- Deuterium-labeled Penicillin V for quantitative analysis.
- Inhibits the growth of Streptococci, C. difficile, and S. aureus.
- Suitable for research on otitis, sinusitis, pharyngitis, and tonsillitis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence pharmacokinetic and metabolic profiles of drugs.
![Revvity Health Sciences Inc Glucose, D-[6-<sup>3</sup>H(N)]-, 5mCi (185MBq)](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812303.jpg-250.jpg)
Revvity Health Sciences Inc Glucose, D-[6-3H(N)]-, 5mCi (185MBq)
Glucose, D-[6-3H(N)]-, 5mCi (185MBq)
Medchemexpress LLC Dxd-d5 (Exatecan-d5 derivative for ADC) | 1599440-33-1 | 98.9% | 498.51 | 1 ML
Dxd-d5 is a deuterium labeled Dxd, which is a potent DNA topoisomerase I inhibitor with an IC50 of 0.31 μM. It is used as a conjugated drug of HER2-targeting ADC (DS-8201a).
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
- Intended for research use only.
Medchemexpress LLC DL-Alanine-d3 | 53795-94-1 | 100 MG
DL-Alanine-d3 is the deuterium labeled DL-Alanine. It is a racemic compound of L- and D-alanine, used as a reducing and capping agent with silver nitrate aqueous solutions for nanoparticle production. It can also be utilized for researching transition metal chelation, such as Cu(II), Zn(II), and Cd(II). DL-alanine functions as a sweetener, classified with glycine and sodium saccharin, and plays a key role in the glucose-alanine cycle between tissues and the liver.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration may impact the pharmacokinetic and metabolic profiles of drugs.
![Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285110.png-250.jpg)
Medchemexpress LLC 3H-imidazo[4,5-f]quinoxalin-2-amine, 8-methyl-3-(methyl-d3) | 122457-31-2 | MFCD00210329 | 99.0% | 216.26 g/mol | C11H8D3N5 | 5 MG
MeIQx-d3 is the triply deuterated isotopologue of MeIQx supplied as a high-purity analytical standard for use as an internal standard and tracer in mass spectrometry and quantitative exposure studies.
- Triply deuterated isotopologue for use as an internal standard.
- High purity: 99.0%.
- Molecular formula C11H8D3N5; molecular weight 216.26 g/mol.
- Available as a 5 MG powder package.
- Storage: powder -20°C; in solvent -80°C for 6 months or -20°C for 1 month.
- Applications include LC-MS/MS quantitation, tracer studies, and method development.
Medchemexpress LLC Glycine-d3 | 4896-76-8 | 100.0% | 78.09 g/mol | C2H2D3NO2 | 10mg
Glycine-d3 is the deuterium labeled Glycine Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors
Medchemexpress LLC Cyclosporin A-13C2,d4 | 59865-13-3 | 95.2% | 500 UG
Cyclosporin A-13C2,d4 is a 13C labeled Cyclosporin A. This immunosuppressant binds to cyclophilin and inhibits the phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM. It also inhibits CD11a/CD18 adhesion. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules for quantitation during drug development.
- Functions as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Adenosine-d1 | 109923-50-4 | 99.7% | 268.25 g/mol | C10H12DN5O4 | 10 MG
Deuterium-labeled adenosine used as a tracer or internal standard for quantitative analytical methods such as LC-MS, GC-MS, and NMR. Supplied as a white to off-white solid with high purity and specified storage conditions to maintain stability.
- Deuterium-labeled adenosine for tracer and internal standard use.
- High purity (99.7%) suitable for analytical applications.
- Soluble in DMSO with ultrasonic warming; compatible with LC-MS, GC-MS, and NMR.
- Powder stability: up to 3 years at -20°C; follow solvent storage guidelines for solutions.
![Revvity Health Sciences Inc ATP, [γ-<sup>32</sup>P]- 10Ci/mmol 2mCi/ml , 1 mCi](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502812791.jpg-250.jpg)
Revvity Health Sciences Inc ATP, [γ-32P]- 10Ci/mmol 2mCi/ml , 1 mCi
ATP, [γ-32P]- 10Ci/mmol 2mCi/ml , 1 mCi
Revvity Health Sciences Inc Internal Standard Kit, 14C-W for Aqueous Samples
Internal Standard Kit, 14C-W for Aqueous Samples
Medchemexpress LLC 1-Hexadecanol-d5 | 1219799-18-4 | 99.2% | 50 MG
1-Hexadecanol-d5 is a deuterium labeled version of 1-Hexadecanol, which is a fatty alcohol and a lipophilic substrate.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Cobimetinib-d4 hydrochloride | MFCD22124461 | 99.3% | 571.8 g·mol⁻¹ | C21H18D4ClF3IN3O2 | 5 MG
Cobimetinib-d4 hydrochloride is the deuterium-labeled hydrochloride salt of cobimetinib, supplied as a high-purity solid for research and analytical use. It is intended for use as an isotopically labeled reference standard or internal standard in assay development and quantitative analysis.
- Deuterium-labeled hydrochloride salt for isotopic tracing and standards.
- High reported purity: 99.3%.
- Molecular formula C21H18D4ClF3IN3O2; molecular weight 571.8 g·mol⁻¹.
- Supplied as a solid; follow recommended storage conditions for stability.
- Available in small milligram quantities suitable for analytical workflows.
- Suitable as an internal standard for LC-MS/MS and other quantitative methods.
Medchemexpress LLC Erlotinib-d6 hydrochloride | 1189953-78-3 | 98.1% | 10MG
Erlotinib-d6 hydrochloride | 1189953-78-3 | 98.1% | 10MG
Medchemexpress LLC Retinyl acetate-d4 | 118139-40-5 | 332.51 | 1 MG
Retinyl acetate-d4 is the deuterium-labeled Retinyl acetate. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemopreventive activities. This compound has potential antineoplastic and chemopreventive activities.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.